Grape seed extract is a natural plant substance that has a concentrated source of oligomeric proanthocyanidins(OPC). It may help skin wounds heal faster and with less scarring. It (OPC) is the most used anti-oxidant in both health foods and cosmetics. OPC is known to clear up oxygen free radical effectively, fighting against senium. It also has a very good performance in lowering cholesterol. Grape seed extract can anti-inflammatory, anti-arthritic and anti-allergic activities, prevent skin aging and inhibit UV radiation-induced peroxidation activity. More important, grape seed extract can penetrate the blood-brain barrier to help protection of the brain and nerve tissue from oxidation.